Reproducibility of 24-h ambulatory blood pressure and measures of autonomic function.

Morrin, Niamh M; Stone, Mark and Henderson, Keiran (2017) Reproducibility of 24-h ambulatory blood pressure and measures of autonomic function. Blood Pressure Monitoring. ISSN 1359-5237, 1473-5725

[img] Text (The full text cannot be supplied for this item)
Published Version. Reproducibility of 24-hour ambulatory blood pressure & measures of autonomic function. Niamh Morrin.docx - Accepted Version
Restricted to Repository staff only until 25 January 2018.
Available under License Creative Commons Attribution Non-commercial.

Download (57kB) | Request a copy
Official URL:


Determining the number of familiarization sessions required for accurate recordings of ambulatory blood pressure monitoring and autonomic function is a prerequisite for the appropriate design of intervention studies. The benefit of familiarization trials remains largely unexplored. The objective of the current investigation was to assess the reproducibility of 24-h ambulatory blood pressure, 24-h heart rate variability (HRV) and resting measurements of HRV and blood pressure variability (BPV). Eleven prehypertensive and hypertensive adults participated. Ambulatory blood pressure and HRV were measured across 24 h on four occasions. In addition, 5-min resting measures of HRV and BPV were recorded and analysed. Variability between consecutive pairs of trials was calculated. The typical error induced by ambulatory recordings of systolic blood pressure reduced over time (3.8-2.8 mmHg). The greatest effect of familiarization was observed at night. Ambulatory HRV was more reproducible than resting measures. The most reproducible markers were root mean square of successive differences [coefficient of variation (CV): 13.2-10%] and high frequency normalized units (CV: 15.2-6.4%), with the percentage of adjacent NN intervals differing by more than 50 ms showing the poorest reproducibility (CV: 23.9-20.7%). Overall BPV (SD) was more reproducible than the frequency domain low frequency component. Familiarization trials are required for the most accurate recordings of both 24-h ambulatory blood pressure monitoring and HRV. Ambulatory HRV provide superior reproducibility to resting measurements.

Item Type: Article
Keywords: Ambulatory Blood Pressure Monitoring, Heart Rate Variability, Blood Pressure Variability, Reproducibility
Members: Bucks New University
Depositing User: Ms Jackie McPeak
Date Deposited: 02 Mar 2017 11:59
Last Modified: 12 Apr 2017 09:06

Actions (login required)

Edit Item Edit Item